Objectives: Numerous studies had been achieved to elucidate the risk factors of osteoporotic vertebral fracture (OVF) such as bone mineral density, age, steroid, smoking history. However, studies about the risk factors of multiple osteoporotic vertebral fractures are rare. Authors evaluated the risk of multiple osteoporotic vertebral fractures.
Methods: Among 527 patients with vertebral fractures from January 2008 to April 2015 in our hospital, 160 patients were enrolled except 367 patients who had non- OVF and lack of data. There were divided into 3 groups; less than 3 acute OVF with no other old OVF (Group 1), greater than or equal to 3 OVF regardless of time of occurrence (Group 2), greater than or equal to 3 acute OVF which occur at the same time (Group 3). We performed a logistic regression analysis as statistical method.
Results: The mean age of the patients was 71.5 ± 11.4 years. There are 23 male patients (14.5%), 137 female patients (85.5%). the mean body mass index was 23.48 ± 3.64, the mean bone mineral density (T-score) was ?2.99 ± 1.17 in the spine, ?2.37 ± 1.08 in the hip. There were no statistically significant in these risk factors; BMI, RA presence, steroid treatment status, smoking, alcohol, treatment of osteoporosis before and after osteoporotic vertebral fractures. However, odds ratio of multiple osteoporotic vertebral fracture was 1.22 higher in their 70s (p = 0.02), 1.38 higher in aged 80 or older than in less than 60 (p < 0.01), 1.78 higher in who has osteoporosis (?2.5 < T-score
Conclusions: Person who has lower bone mineral density or elderly person are associated with multiple osteoporotic vertebral fractures.
|